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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0664 All Species: 20
Human Site: Y1173 Identified Species: 36.67
UniProt: O75153 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75153 NP_056044.3 1309 146670 Y1173 L Q H E K E G Y T I Y K T Q L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548323 1501 166268 Y1365 L Q H E K E G Y T V Y K T Q L
Cat Felis silvestris
Mouse Mus musculus Q5SW19 1315 148050 Y1175 L Q H E K E G Y T I Y K T Q L
Rat Rattus norvegicus XP_001080615 1352 151608 Y1216 L Q H E K E G Y T I Y K T Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509391 982 108607 K855 F F Q S G Q A K V Q Q G F L K
Chicken Gallus gallus XP_415920 1293 145294 L1166 L R F L E N A L A I S S K Y H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A0JMD0 1400 155792 E1271 R V Y E S K A E F R S A L Q H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAB5 1448 160833 Y1298 L N N E K E T Y S F Y K S Q L
Honey Bee Apis mellifera XP_624898 1290 145677 H1163 L K V A V S Y H L V A R T Q S
Nematode Worm Caenorhab. elegans P34466 1247 139903 L1116 P R K L K T G L I S N L I A R
Sea Urchin Strong. purpuratus XP_001198284 1101 124381 G974 R E F C S K L G V Q L L L R D
Poplar Tree Populus trichocarpa XP_002314020 1343 146561 Y1126 A Q H E K K T Y D I L V K Q L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RY84 1211 135142 L1061 R R W F E E S L R V C N K V F
Conservation
Percent
Protein Identity: 100 N.A. N.A. 83.3 N.A. 94.9 89.9 N.A. 60.8 83.1 N.A. 75 N.A. 52 59.8 39.9 51.9
Protein Similarity: 100 N.A. N.A. 85.5 N.A. 96.9 92.7 N.A. 67.2 89.3 N.A. 83.6 N.A. 69 75.7 59.5 63.7
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 100 100 N.A. 0 13.3 N.A. 13.3 N.A. 60 20 13.3 0
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 6.6 26.6 N.A. 26.6 N.A. 80 46.6 20 20
Percent
Protein Identity: 27.3 N.A. N.A. N.A. N.A. 29
Protein Similarity: 46.6 N.A. N.A. N.A. N.A. 48.9
P-Site Identity: 53.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 60 N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 0 0 24 0 8 0 8 8 0 8 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % D
% Glu: 0 8 0 54 16 47 0 8 0 0 0 0 0 0 0 % E
% Phe: 8 8 16 8 0 0 0 0 8 8 0 0 8 0 8 % F
% Gly: 0 0 0 0 8 0 39 8 0 0 0 8 0 0 0 % G
% His: 0 0 39 0 0 0 0 8 0 0 0 0 0 0 16 % H
% Ile: 0 0 0 0 0 0 0 0 8 39 0 0 8 0 0 % I
% Lys: 0 8 8 0 54 24 0 8 0 0 0 39 24 0 8 % K
% Leu: 54 0 0 16 0 0 8 24 8 0 16 16 16 8 47 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 0 0 8 0 0 0 0 8 8 0 0 0 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 39 8 0 0 8 0 0 0 16 8 0 0 62 0 % Q
% Arg: 24 24 0 0 0 0 0 0 8 8 0 8 0 8 8 % R
% Ser: 0 0 0 8 16 8 8 0 8 8 16 8 8 0 8 % S
% Thr: 0 0 0 0 0 8 16 0 31 0 0 0 39 0 0 % T
% Val: 0 8 8 0 8 0 0 0 16 24 0 8 0 8 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 8 47 0 0 39 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _